M: Marginal erosions
O: Osteopenia
B: Bilaterally symmetrical
S: Subluxation
S: Swelling
S: Symmetrical joint space narrowing
O: Osteopenia
B: Bilaterally symmetrical
S: Subluxation
S: Swelling
S: Symmetrical joint space narrowing
Radiographic findings of RA
Note:MOBs^3
NSAIDs (COX-2)
Corticosteroids
DMARDs (methotrexane, TNF-a antagonists, hydrochloroquine & sulfasalazine)
Corticosteroids
DMARDs (methotrexane, TNF-a antagonists, hydrochloroquine & sulfasalazine)
Treatments (3)
1. Fibular deviation
2. Swan neck
3. Ulnar deviation
4. Digital contractures
5. Prominent met heads
6. Rheumatoid nodules
2. Swan neck
3. Ulnar deviation
4. Digital contractures
5. Prominent met heads
6. Rheumatoid nodules
Articular manifestations (6)
1. Inflammation of synovium
2. Injury to the synovial microvasculature (earliest)
3. Mild hyperplasia
4. Pannus
5. Marginalerosion
6. Uniform loss of joint space
2. Injury to the synovial microvasculature (earliest)
3. Mild hyperplasia
4. Pannus
5. Marginalerosion
6. Uniform loss of joint space
Clinical presentation (6)
What is the earliest changes
Vasculitis
C: Cricoarytenoid joint inflammation
C: Cervical spine instability
H: Hypochromic microcytic anemia
I: Interstitial lung disease
P: Peripheral nerve entrapment
P: Pericardial effusion
S: Sjodren syndrome
C: Cricoarytenoid joint inflammation
C: Cervical spine instability
H: Hypochromic microcytic anemia
I: Interstitial lung disease
P: Peripheral nerve entrapment
P: Pericardial effusion
S: Sjodren syndrome
Manifestations of RA if left untreated
