Skin Infections- Test 4

B. S. pyogenes.
In addition to S. aureus, impetigo may also involve

A. M. luteus.

B. S. pyogenes.

C. S. epidermidis.

D. Pseudomonas spp.

E. Rocky Mountain spotted fever
. In which of the following does a rash start on the palms and soles and progress toward the trunk?

A. Epidemic typhus

B. Typhoid

C. Lyme disease

D. Impetigo

E. Rocky Mountain spotted fever

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D. Dermacentor andersoni.
. The major vector of Rocky Mountain spotted fever in the western U.S. is

A. Rickettsia rickettsi.

B. Rickettsia prowazeki.

C. Borrelia burgdorferi.

D. Dermacentor andersoni.

D. zoonosis.
Rocky Mountain spotted fever is an example of a(n)

A. animalosis.

B. tickonosis.

C. plantonosis.

D. zoonosis.

D. within 4-10 hours.
. After being bitten by an infected tick, transfer of the rickettsial organism occurs

A. immediately.

B. within 5 minutes.

C. within 20 minutes.

D. within 4-10 hours.

C. Rickettsia rickettsi
. Which of the following is an obligate intracellular parasite?

A. M. luteus

B. S. pyogenes

C. Rickettsia rickettsi

D. Pseudomonas spp.

C. Borrelia burgdorferi.
The causative agent of Lyme disease is

A. Rickettsia rickettsi.

B. Rickettsia prowazeki.

C. Borrelia burgdorferi.

D. Dermacentor andersoni.

A. erythema migrans.
(means migrating redness)
. The unique characteristic of Lyme disease is

A. erythema migrans.

B. induration.

C. carbuncle.

D. furuncle.

B. third.
. The stage of Lyme disease that is characterized by arthritis is the

A. primary.

B. third.

C. second.

D. fourth.

D. Ixodes scapularis.
. The most important vector of Lyme disease in the eastern U.S. is

A. Dermacentor virabilis.

B. Dermacentor andersoni.

C. Staphylococcus aureus.

D. Ixodes scapularis.

C. spirochete
. Which of the following pertains to Borrelia burgdorferi?

A. coccus

B. bacillus

C. spirochete

D. filament

B. white-footed mouse.
. The preferred host of Ixodes scapularis is the

A. wood rat.

B. white-footed mouse.

C. moose.

D. human.

A. nymph stage.
. The growth stage of the vector that is mainly responsible for transmitting Lyme disease is the

A. nymph stage.

B. egg.

C. moulter.

D. adult.

A. inspection of the rash.
Many childhood diseases caused by viral infections of the upper respiratory tract can usually be diagnosed by

A. inspection of the rash.

B. the type of cough.

C. the type of fever.

D. the incubation period.

D. varicella.
A common viral rash of childhood with the popular name chicken pox is also known as

A. bariola.

B. rubella.

C. rubeola.

D. varicella.

D. herpes
The varicella virus is a member of which virus family?

A. paramyxo

B. toga

C. papilloma

D. herpes

A. shingles.
. Reactivation of chickenpox is called

A. shingles.

B. herpes zoster.

C. pneumonia.

D. exanthems.

E. shingles AND herpes zoster.

B. measles.
. The childhood disease that damages the body defenses and is frequently complicated by secondary infections involving, primarily, Gram-positive cocci is

A. German measles.

B. measles.

C. mumps.

D. chickenpox.

D. single-stranded RNA.
. The rubeola virus contains

A. double-stranded RNA.

B. single-stranded DNA.

C. multiple pieces of single-stranded, negative-sense RNA.

D. single-stranded RNA.

B. the respiratory route.
Rubella, rubeola and varicella-zoster are all only acquired via

A. the gastrointestinal route.

B. the respiratory route.

C. wounds.

D. blood transfusions.

A. Koplik’s spots.
. An important diagnostic sign of measles is

A. Koplik’s spots.

B. giant cells.

C. fever.

D. swollen lymph nodes.

D. measles, mumps, rubella.
. The MMR vaccine is used to protect against

A. mononucleosis, mange, rubeola.

B. measles, mange, rubeola.

C. mononucleosis, mumps, rubella.

D. measles, mumps, rubella.

D. birth defects.
. The most serious consequence of rubella is

A. encephalitis.

B. meningitis.

C. deafness.

D. birth defects.

C. togavirus
Rubella is a member of which virus family?

A. paramyxo virus

B. herpes

C. togavirus

D. papovavirus

A. papillomavirus.
. Warts are caused by

A. papillomavirus.

B. parvovirus.

C. papovavirus.

D. herpes virus.

Streptococcus pyogenes- Impetigo
A three year old developed a series of blister like lesions around her nose and mouth. The lesions remained localized to the area and began to scab over the next couple of days. However the parents grew concerned when the second child developed the same kind of lesions
Numerous gram positive cocci in chain and numerous pus cells
Culture shows large number of group A beta hemolytic streptococci and a few Staph aureus
What is the most likely diagnosis of the disease ?
A- Skin
Your patient has a subacute bacterial endocarditis caused by the a number of the viridans group of Streptococci. Which one of the following sites is MOST likely to be the source of the organism
A- Skin
B- Colon
C- Oropharynx
D- Urethra
True
The very low humidity of the desert would lead to rapid evaporation of sweat and sebum from an individual’s skin. Bacteria need these secretions for a nutrient source. Without them, bacteria would be found in much lower numbers on the skin of a person in the desert than the skin of the person in the tropics.
True False
-True
-True
-True
-True
. Borrelia burgdorferi is a spirochete with a number of axial filaments.

True False

. Varicella is a member of the herpes family of viruses and produces a latent infection.

True False

. Humans are the only reservoir for varicella-zoster.

True False

. Complications of measles may include pneumonia and encephalitis.

True False

.

-True
-True
Chickenpox and measles are both acquired by the respiratory route.

True False

. The MMR vaccine is used to protect against measles, mumps, and rubella.

True False

-Rubella can spread to placenta, causing birth defects or stillbirth.
-True
-False
1 A public health official was asked to speak about immunizations during a civic group luncheon. One parent asked if rubella was still a problem. In answering the question, the official cautioned women planning to have another child to have their present children immunized against rubella. Why did the official make this statement to the group?

. Rubella is spread very easily by respiratory secretions and is largely asymptomatic. However, it can cause birth defects/stillbirth in pregnant women. Women with other children would want to prevent these children from acquiring the virus before attempting to conceive a new child in order to protect the fetus.

True False

. The official is getting kickbacks and bribes from the companies making the vaccines, and he’s trying to pad his pockets by getting as many people immunized as possible, regardless of whether they need it or not.
True False

-The lyme disease does not spread by contact
-False
-False
-True
-False
2

. When Lyme disease was first being investigated, the observation that frequently only 1 person in a household was infected was a clue leading to the discovery that the disease was spread by arthropod bites. Why was this so?

. Mosquitoes (an example of arthropods) are never inside a house. They are strictly outdoor animals, so they couldn’t spread the infection inside the household
True- False.

. Mosquitoes (an example of arthropods) only bite once in their life cycle. As such, they can only transmit the illness once before they die. Even if an infected mosquito was inside a house, it could therefore only infect one human.
True False

. If the infection is spread by the bite of an arthropod, it wouldn’t spread easily by respiratory secretions, direct contact, or sexual contact between individuals within the family.
True False

. Arthropods lose their mechanical ability to bite a human after a single bite, much like certain bees that lose their stinger after a single sting. This prevents them from transmitting the infection to more than one individual in a household.
True False

-True
-False
-False
-True
-True
– What is the epidemiological significance of shingles?

. It shows that, as a latent viral infection, there is always a possible reservoir available to reinfect new susceptible individuals.
True False

. It shows that we must always be vigilant against this deadly and highly infectious secondary infection in elderly and immunocompromised individuals.

.

True False

It shows that, as a chronic viral infection, individuals infected are always infectious to others around them, even when they do not show outward symptoms.

. True Talse

It shows that our fight for long-term eradication of varicella zoster virus will be a very long fight, depending on immunizing all newly-born individuals until all the people that had ever contracted the illness have died.

. True False

It shows that, as a latent viral infection, there is always a possible reservoir available to reinfect new susceptible individuals AND it shows that our fight for long-term eradication of varicella zoster virus will be a very long fight, depending on immunizing all newly-born individuals until all the people that had ever contracted the illness have died.
True Fase

-Streptococcus progenies group A, Beta hemolytic (GAS)- gram positive cocci.
-Strep throat can cause impetigo
-May cause type 3 allergic reaction if not treated with antibiotics.
– forms an antigen/antibody complex that goes to the glomerulus causing acute glomerulonephritis (no more transfer of fluids in kidney)
-symptoms: fluid retention, fever, high BP, blood and protein in urine.
Impetigo:
-treat with STEROIDS (penicillin before this happens).
Treatment of impetigo
-Caused by rickettsia rickets (intracellular bacterium- gram negative- endotoxin is LPS)
-Transmitted by a bite of an infected wood tick (dermacentor andersoni)
-Comes from the wood ticks saliva to our endothelia cells (lining of our blood vessels)
-Red spots on skin due to lysing of infected endothelial cells.
-Takes 4 to 10 hours to transmit bacteria from saliva
Rocky Mountain Spotted Fever
-Must be treated with tetracycline and chloramphenicol.
Treatment of rocky mountain spotted fever
-Caused by bacteria barrel burgodorferri (spirochete)- goes into tissue and blood.
– Comes from black legged tick (Ixodes Scapularis)
-Symptoms: rash (erythema migrans), flu-like symptoms, arthritis, nervous system problems if not treated)
-can not be transferred from people to people.
Lyme Disease
-Treated with doxycycline.
Treatment of lyme disease
Contracted with inhaling.
Viral skin diseases
-Caused by Varicella Zoster Virus (VSV)
-Childhood disease
-inhaled, comes from scratching scabs and breathing in.
-adaptive immunity created if caught
-can become latent and reactivate (from sensory ganglia on spine) to SHINGLES
-If mom gets shingles, can be passed on to baby.
Chickenpox
(1) Macule- flat redness of skin- VSV in skin
(2) Papule- elevated redness of skin
(3) Blister- itchy, lyse of VSV and neutrophils
(4) Scratch the blister- turns into ulcer- VSV goes into air
Steps of chickenpox
attentuated vaccine
-Zoster Immune globulin for elderly.
Vaccine for chickenpox
-caused by rubeola virus (paramyxovirus family- single-stranded RNA)
-Childhood disease-
-higher fever, damages mucosilliary elevator– disease goes towards bronchi (get bronchitis)
-Koplik’s spots on tongue.
-T cytotoxic cells kills viral cells causing rash
– Can cause lung and brain damage.
-MMR vaccine
Measles
-mild disease
-redness on skin caused by type 3 allergic reaction (an antigen/antibody reaction)
-known to cause an congenital rubella syndrome- birth defects
-no treatment
-MMR vaccine
German measles (rubella)
-Caused by human papillomaviruses
-Generally benign skin tumors
-Some are associated with uterine cervix cancer- may also cause cancer in males
-suppress tumor suppressing genes.
Warts
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